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First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis. But this is temporary, and will eventually end up tightening the skin around the eyelids, provided you are using a potent retinol preparation.
Vitamin "A" serum, a retinaldehyde which is very similar to Retin-A (a prescription product) in efficacy but does not cause the irritation of Retin-A.
