Latest research shows that decline of the brain is not inevitable. While the brain volume shrinks slightly, it continues to make new neurons and fine tune connections as long as we live. Anti-aging studies show we still can learn as we age.
The best way to reduce brain loss and deep cognitive abilities sharp is aerobic exercise, which slashes the lifetime risk of Alzheimer's disease in half and the risk of dementia by 60%.
Exercise boosts the flow of blood to the brain, releasing what's been called "Miracle-Gro for the brain" - brain derived neurotrophic factor (BDNF). This chemical stimulates the formation of new neurons in the hippocampus, the area involved in memory, learning and the ability to plan and make decisions. BDNF also repairs cell damage and strengthens the synapses which connects brain cells.
Studies over the last few years show that everyone, young or old, can increase brain power by aerobic exercising regularly. Exercising aerobically, even in late adulthood and even if you have not been active before, is not futile. Dementia is not inevitable.
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First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis. But this is temporary, and will eventually end up tightening the skin around the eyelids, provided you are using a potent retinol preparation.